How to Use and Interpret Serological Tests for EPM and Lyme Disease

EMP and Lyme serologic testsAmy L. Johnson, DVM, DACVIM (LAIM & Neurology)

Serological tests for equine protozoal myeloencephalitis (EPM) and Lyme disease are probably the most commonly submitted tests for horses with neurologic disease, gait deficits, or poor performance. Whether these ancillary tests are helpful or misleading depends on the veterinarian’s ability to interpret results accurately, with consideration of the specifics of the case.

This two-part course consists of one proceedings paper and the accompanying 2019 AAEP Convention presentation. The video has been split into two parts for ease of download and viewing; as one video part concludes, the next will unlock.

You must view all sections of the course before the quiz will unlock.

Course objectives:

With the successful completion of this course, you will understand

  • common symptoms and EPM and Lyme Disease
  • standard diagnostic tests 
  • the challenge of correct application and interpretation of tests
  • methods of interpreting test results to minimize unnecessary treatment

Continuing education credit:

  • 0.5 credit hour Medical, Non-interactive/Anytime, with a passing score of at least 70%

Approximate duration:

  • 30 minutes: read the paper, view the presentation, complete the quiz


  • Read the paper from the 2019 AAEP Convention proceedings, approximately 2,300 words
  • View the presentation from the 2019 AAEP Convention, 21 minutes
  • Complete quiz
How to Use and Interpret Serological Tests for EPM and Lyme Disease00:40:45
View Presentation, Part 1 00:08:00
View Presentation, Part 2 00:12:45
Read the paper from the 2019 AAEP Convention Proceedings 00:20:00
Pass the quiz to earn CE credit
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